Multiple non-collinear TF-map alignments of promoter regions |
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Authors: | Enrique Blanco Roderic Guigó Xavier Messeguer |
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Institution: | 1.Grup d'Algorísmica i Genètica. Departament de Llenguatges i Sistemes Informàtics,Universitat Politècnica de Catalunya,Barcelona,Spain;2.Bioinformatics and Genomics Program,Centre de Regulació Genòmica.Pg,Barcelona,Spain |
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Abstract: | Background The analysis of the promoter sequence of genes with similar expression patterns is a basic tool to annotate common regulatory
elements. Multiple sequence alignments are on the basis of most comparative approaches. The characterization of regulatory
regions from co-expressed genes at the sequence level, however, does not yield satisfactory results in many occasions as promoter
regions of genes sharing similar expression programs often do not show nucleotide sequence conservation. |
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Keywords: | |
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