Rearrangements of chromosome region 12q13----q15 in pleomorphic adenomas of the human salivary gland (PSA) |
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| Authors: | J Bullerdiek S Bartnitzke M Weinberg R Chilla J Haubrich W Schloot |
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| Institution: | Centre of Human Genetics and Genetic Counselling, University of Bremen, Federal Republic of Germany. |
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| Abstract: | Nine of 40 pleomorphic salivary gland adenomas (PSAs) showed clonal aberrations of chromosome 12, with a breakpoint at 12q13----q15. The cytogenetic findings in these cases and those of nine additional cases reported in the literature suggest that this type of aberration is a primary change directly involved in the genesis of PSA. |
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