| Th17细胞在肺部感染免疫中的作用 |
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| 引用本文： | 王慧芳,王斯,吴发玲,施小妹.Th17细胞在肺部感染免疫中的作用[J].微生物学杂志,2009,29(3):50-53. |
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| 作者姓名： | 王慧芳 王斯 吴发玲 施小妹 |
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| 作者单位： | 1. 中国医科大学,附属盛京医院,辽宁,沈阳,110004
2. 中国医科大学,基础医学院病原生物学教研室,辽宁,沈阳,110001 |
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| 摘 要： | Th17细胞是近年来发现的一种新的效应T细胞亚群，在自身免疫性疾病和感染中发挥重要的作用，其分泌产生几种致炎细胞因子，包括新发现的细胞因子白细胞介素17。Th17产生的细胞因子与Th1、Th2不同并且与其相互对抗。Th17细胞很可能对防御胞外病原菌的感染及自身免疫性疾病产生影响。综述了Th17细胞产生的细胞因子及其在肺部感染免疫中的作用相关方面的进展。
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| 关 键 词： | Th17细胞 白细胞介素17 肺部感染 |
Role of Th17 Cells in Immunity Against Pulmonary Infection |
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| WANG Hui-fang,WANG Si,WU Fa-ling,SHI Xiao-mei.Role of Th17 Cells in Immunity Against Pulmonary Infection[J].Journal of Microbiology,2009,29(3):50-53. |
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| Authors: | WANG Hui-fang WANG Si WU Fa-ling SHI Xiao-mei |
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| Institution: | WANG Hui-fang,WANG Si, WU Fa-ling, SHI Xiao-mei (The Seven-Year-System Department of Chinese Medical University, Shenyang 110004 ) |
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| Abstract: | Th17 (T helper 17 cel1), a newly discovered subpopulation of T lymphocytes, was confirmed to play a critical role in inflammatory and autoimmune diseases. This subpopulation produces several proinflammatory cytokines including a novel interleukin named as IL-17. The cytokines produced by Th17 cells differed from those by and Th1 and Th2 cells, and exhibits antagonistic effects among them. Th17 cells are probably effective to resist infections caused by extracellular bacteria. This paper discussed the cytokines produced by th17 cells and the function of cytokins in immunity against pulmonary infection. |
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| Keywords: | Th17 cell Interleukin-17 Pulmonary infection |
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