Some applications of a chiral fluorometric reagent, (S)-TBMB carboxylic acid |
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Authors: | Meguro H Kim J H Bai C Nishida Y Ohrui H |
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Institution: | Kansei Fukushi Research Center, Tohoku Fukushi University, 1-8-1 Kunimi, Aoba-ku, Sendai 981-0943, Japan. meguro@tfu-mail.tfu.ac.jp |
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Abstract: | Molecular design and applications of a fluorometric chiral agent, (S)-TBMB carboxylic acid, are briefly reviewed. The agent, possessing an asymmetric 1,3-benzodioxole skeleton, was designed as a novel class of chiral agent that functions also as a benzoate chromophore for exciton chirality CD methods. The utility of this agent has been demonstrated in an application to determine enantiomeric amino acids, acyl-sn-glycerols, glycosyl-sn-glycerols, and other chiral alcohols and amines. |
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