Chromosomal localization of HSP70 genes in cattle |
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| Authors: | Daniel S Gallagher Jr Michael D Grosz James E Womack Loren C Skow |
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| Institution: | (1) Department of Veterinary Pathobiology, Institute of Biosciences and Technology, Texas A&M University, 77843 College Station, Texas, USA;(2) Center for Animal Genetics, Institute of Biosciences and Technology, Texas A&M University, 77843 College Station, Texas, USA;(3) Department of Veterinary Anatomy and Public Health, Texas A&M University, 77843 College Station, Texas, USA;(4) Present address: USDA-ARS, U.S. Meat Animal Research Center, 68933 Clay Center, Nebraska, USA |
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| Abstract: | Five genomic clones representing three HSP70 genes of cattle were biotin labeled and independently hybridized to cattle chromosomes. Fluorescence in situ hybridization localized HSP70-2 to Chromosome (Chr) 23 band 22 (the BoLA region), HSP70-3 to Chr 10 band 34, and HSP70-4 to Chr 3 band 13. Since HSP70-1, a fourth HSP70 gene, is tightly linked with HSP70-2 and the BOLA@, HSP70-1 was also localized to Chr 23 band 22. The localization of HSP70-4 is the first assignment of a cattle U6 marker; thus, this entire syntenic group is tentatively placed in cattle Chr 3. |
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