Nuclear migration and positioning in filamentous fungi |
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| Authors: | Xiang Xin Fischer Reinhard |
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| Affiliation: | Department of Biochemistry and Molecular Biology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA. xxiang@usuhs.mil |
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| Abstract: | Genetic analyses of nuclear distribution mutants have indicated that functions of the microtubule motor, cytoplasmic dynein, and its regulators are important for nuclear positioning in filamentous fungi. Here we review these studies and also present the need to further dissect how dynein and its associated microtubule cytoskeleton are involved mechanistically in nuclear positioning in the multinucleated hyphae. |
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