| 斑马鱼生物钟研究进展 |
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| 引用本文： | 王明勇,黄国栋,王晗.斑马鱼生物钟研究进展[J].遗传,2012,34(9):1133-1143. |
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| 作者姓名： | 王明勇 黄国栋 王晗 |
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| 作者单位： | 苏州大学生物钟研究中心, 苏州 215123 |
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| 基金项目： | 国家自然科学基金重点项目,国家重大科学研究计划,江苏特聘教授计划和苏州大学科研启动经费 |
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| 摘 要： | 斑马鱼是生物钟研究领域中一种新兴的脊椎动物模型。文章总结了斑马鱼生物钟研究的一些进展, 以及利用斑马鱼研究生物钟的特点及优势。由于光照和温度作为重要的外部信号在斑马鱼生物钟调节中发挥重要作用, 文章主要就近期光和温度对斑马鱼钟基因及调节通路的研究进行了概述, 最后对斑马鱼生物钟研究的未来提出了展望。
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| 关 键 词： | 生物钟 负反馈环路 光调节 温度补偿 斑马鱼 |
| 收稿时间： | 2012-03-03 |
Advances in the zebrafish circadian clock mechanisms |
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| WANG Ming-Yong,HUANG Guo-Dong,WANG Han.Advances in the zebrafish circadian clock mechanisms[J].Hereditas,2012,34(9):1133-1143. |
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| Authors: | WANG Ming-Yong HUANG Guo-Dong WANG Han |
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| Institution: | Center for Circadian Clocks, Medical College, Soochow University, Suzhou 215123, China |
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| Abstract: | Zebrafish has recently become an emerging vertebrate model for circadian studies.Here we summarized re-cent advances in the field of zebrafish circadian research.The characteristics and advantages of zebrafish as a circadian model,as well as its time-keeping mechanisms,were highlighted.Because light and temperature as external time cues both play important roles in the circadian regulation of zebrafish,we focused on recent studies concerning the effects of light and temperature on circadian clock genes and circadian regulatory pathways in zebrafish.We also provided the perspectives on prospective zebrafish circadian studies. |
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| Keywords: | circadian clocks negative feedback loop light regulation temperature compensation zebrafish |
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