基底节区脑梗塞的神经心理学和听觉事件相关诱发电位的研究

目的：了解基底节区脑梗塞（BGRI）患者发病后记忆力和视空间能力的状况,分析BGRI是否对认知功能产生影响及其特点。方法：通过对21名初发的单侧单灶BGRI及21位年龄、性别、受教育程度相匹配的基本健康志愿者分别进行Rey复杂图形检查（Rey）,临床记忆量表（CMS）、Hospital Anxiety-Depression Scale（HAD）,美国国立卫生研究院卒中量表（NIHSS）、牛津残障量表（OHS）、Barthel指数（BI）及听觉事件相关诱发电位（AERP）的检查。结果：病例组的焦虑及抑郁分值,具有极显著的统计学意义;AERP检查反应时较对照组长,具有显著的统计学意义;在临床记忆量表中,病例组图像自由回忆分测验的量表分和记忆商（MQ）较差,与对照组相比有显著统计学意义。病例组Rey检查中临摹得分、即刻回忆得分和延迟回忆得分与对照组比较无显著性差异。结论：单侧单灶的基底节区脑梗塞可以对执行功能、记忆能力以及情绪造成影响：对视空间功能的影响不大.

Study of the neuropsychology and aural event related evoked potential on patients with the infarction in basal ganglia region

Aim:To learn the condition of the memory and the visual space of the patient who has suffered from the infarction in basal ganglia region,and to analyze its impact on and the characteristics of the patients' cognition.Methods:By testing respectively on 21 subjects who were initially infarcted in basal ganglia with single focus on one side,and 21 healthy volunteers with corresponding age,gender and educational background with Rey-Osterrieth Complex Figure Scale(Rey),Clinical Memory Scale(CMS),Hospital Anxiety-Depression Scale(HAD),National Institute of Health Stroke Scale(NIHSS),Oxford Handicap Scale(OHS),Barthel Index(BI),and Aural Event Related Evoked Potential(AERP) as well.Results:Compared with the control group,the patient group got higher scores of anxiety and depression in HAD,which showed absolutely statistical significance;they demonstrated longer reaction time in AERP,which also showed statistical significance;and in CMS,they displayed inferior performance in the free picture recall and the memory quotient(MQ),which again had statistical significance.However,compared with the control group,the patient group got scores with no significance in copy,immediate recall and delayed recall in Rey.Conclusion:The infarction in basal ganglia region with single focus on one side may impact on the patient's executive function,memory function and emotion.But no impact is showed on patient's visual space function.