| 革兰氏阳性菌细胞外囊泡的研究现状 |
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| 引用本文： | 葛艳艳,李子涵,王新月,罗学刚,王楠,何红鹏,张同存,齐威. 革兰氏阳性菌细胞外囊泡的研究现状[J]. 生物工程学报, 2022, 38(4): 1462-1474 |
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| 作者姓名： | 葛艳艳 李子涵 王新月 罗学刚 王楠 何红鹏 张同存 齐威 |
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| 作者单位： | 天津科技大学 生物工程学院, 天津 300457 |
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| 基金项目： | 国家重点研发计划(2018YFA0901700);国家自然科学基金联合基金(U20A20400) |
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| 摘 要： | 细胞外囊泡(EVs),也称为膜小泡,是真核细胞和细菌分泌的囊泡状小体.它通过携带蛋白质、DNA、RNA和各种代谢物进行细胞间物质的交流传递.根据内容物的不同发挥不同的生理功能,如传递营养物质、参与免疫反应、治疗癌症等.目前大多数研究专注于真核细胞和革兰氏阴性菌囊泡的探索,而对革兰氏阳性菌中分泌的囊泡研究较少.这篇综述总...
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| 关 键 词： | 细胞外囊泡 革兰氏阳性菌 生理功能 相互作用 免疫 |
| 收稿时间： | 2021-07-06 |
| 修稿时间： | 2021-09-08 |
The extracellular vesicles from gram-positive bacteria:a review |
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| GE Yanyan,LI Zihan,WANG Xinyue,LUO Xuegang,WANG Nan,HE Hongpeng,ZHANG Tongcun,QI Wei. The extracellular vesicles from gram-positive bacteria:a review[J]. Chinese journal of biotechnology, 2022, 38(4): 1462-1474 |
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| Authors: | GE Yanyan LI Zihan WANG Xinyue LUO Xuegang WANG Nan HE Hongpeng ZHANG Tongcun QI Wei |
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| Affiliation: | School of Biological Engineering, Tianjin University of Science and Technology, Tianjin 300457, China |
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| Abstract: | Extracellular vesicles (EVs),also known as membrane vesicles,are vesicular bodies secreted by eukaryotic cells and bacteria.EVs can carry proteins,DNA,RNA,and various metabolites for the exchange and transmission of substances between cells.They play contents-dependent physiological functions,such as delivering nutrients,participating in immune response,and treating cancers.Currently,most studies focus on the exploration of vesicles secreted by eukaryotic cells and gram-negative bacteria,while few studies focus on gram-positive bacteria.This review summarized the production,content composition,physiological function,and engineering of EVs secreted by gram-positive bacteria,and prospected future perspectives in this area. |
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| Keywords: | extracellular vesicles Gram-positive bacteria physiological function interaction immunity |
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