| 抗癌药物紫杉醇的全合成—Holton合成紫杉醇路线的剖析 |
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| 引用本文： | 陈巧鸿,王锋鹏. 抗癌药物紫杉醇的全合成—Holton合成紫杉醇路线的剖析[J]. 天然产物研究与开发, 2001, 13(3): 88-95 |
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| 作者姓名： | 陈巧鸿 王锋鹏 |
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| 作者单位： | 华西医科大学药学院天然药物化学教研室,成都,610041 |
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| 摘 要： | 从全合成战略与路线，关键反应，保护基应用和立体化学方面对Holton的线性全合成紫杉醇路线进行剖析归纳。
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| 关 键 词： | 全合成 紫杉醇 Holton法 抗癌药物 合成路线 |
| 修稿时间： | 2000-10-11 |
TOTAL SYNTHESIS OF TAXOL DEVELOPED BY HOLTON |
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| CHEN Qiao Hong,WANG Feng Peng. TOTAL SYNTHESIS OF TAXOL DEVELOPED BY HOLTON[J]. Natural Product Research and Development, 2001, 13(3): 88-95 |
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| Authors: | CHEN Qiao Hong WANG Feng Peng |
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| Abstract: | The review described the total synthesis of taxol developed by Holton,including the synthetic strategy and routes,key reactions,application of protective groups and stereochemistry. |
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| Keywords: | synthesis taxol Holtons approach |
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