| DNA damage: air-breaks? |
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| 引用本文： | Barnes DE. DNA damage: air-breaks?[J]. Current biology : CB, 2002, 12(7): R262-R264. DOI: 10.1016/S0960-9822(02)00788-1 |
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| 作者姓名： | Barnes DE |
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| 摘 要： |
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DNA Damage: Air-breaks? |
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| Barnes Deborah E. DNA Damage: Air-breaks?[J]. Current biology : CB, 2002, 12(7): R262-R264. DOI: 10.1016/S0960-9822(02)00788-1 |
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| Authors: | Barnes Deborah E |
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| Affiliation: | Cancer Research UK London Research Institute, Clare Hall Laboratories, South Mimms, Hertfordshire EN6 3LD, UK. deborah.barnes@cancer.org.uk |
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| Abstract: | Cells deficient in repairing DNA double-strand breaks have an increased level of spontaneous chromosomal aberrations. Modulating the level of molecular oxygen and its reactive metabolites demonstrates that oxygen metabolism is a major source of genomic instability. |
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