Changes in activity of enzymes metabolizing glucose 6-phosphate during development of the basidiomycete Schizophyllum |
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Authors: | M N Schwalb |
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Affiliation: | Department of Microbiology, New Jersey Medical School, Newark, New Jersey 07103 USA |
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Abstract: | During the formation of fruit bodies in the basidiomycete Schizophyllum commune, there are changes in the specific activities of the enzymes utilizing glucose 6-phosphate. These include a 50% increase in the relative amount of glucose-6-phosphate dehydrogenase followed by a decrease in this enzyme and a 90% decrease in phosphoglucomutase activity. This results in a 10-fold change in the relationship between these two enzymes during development. The activities in several mutants were examined and abnormal enzyme levels were found in some cases. The activity of 6-phosphogluconate dehydrogenase was also examined, and its contribution to the assay of the other enzymes was determined. |
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