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Human chymase inhibitors based on the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold. |
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| Authors: | W C Groutas N M Schechter S He H Yu P Huang J Tu |
| Affiliation: | Department of Chemistry, Wichita State University, KS 67260, USA. |
| Abstract: | A series of compounds that utilize the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold was synthesized and shown to be highly effective inhibitors of recombinant human skin chymase. |
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