Autoradiographic studies on glucose utilization in individual zone of the rat thymus |
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Authors: | J. B. Warchol Ch. Pilgrim W. J. Ginda R. Brelińska |
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Affiliation: | (1) Department of Histology and Embryology, Medical Academy, ul. Swiecickiego 6, PL-60-781 Pozna , Poland;(2) Abteilung Anatomie und Zellbiologie der Universität Ulm, Oberer Eselsberg, D-7900 Ulm, Federal Republic of Germany |
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Abstract: | Summary Wistar rats were injected intraperitoneally with 2-(14C)deoxyglucose and their thymuses were processed for thaw-mount autoradiography after 5, 10 or 35 min. Highest levels of radioactivity were demonstrated in the thymic medulla (5-fold higher than in the cortex). Scanning of autoradiograms for regional differences in grain densities indicated particularly intense glucose utilization in the cortico-medullary zone. Differences in glucose utilization between individual thymic zones seem to reflect differences in cellular composition, i. e., ratio of stroma cells to thymocytes.Dedicated to Professor Dr. T.H. Schiebler on the occasion of his 65th birthday |
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