| 兔角膜缘干细胞的研究进展 |
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| 引用本文： | 白靓,周余来,成岩,顾国贞. 兔角膜缘干细胞的研究进展[J]. 现代生物医学进展, 2007, 7(10): 1578-1581,1593 |
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| 作者姓名： | 白靓 周余来 成岩 顾国贞 |
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| 作者单位： | 吉林大学再生医学科学研究所,吉林,长春,130021 |
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| 摘 要： | 目前,角膜移植是临床上治疗角膜疾患的最有效途径,但供体角膜非常有限。新近兴起的干细胞技术,为组织工程角膜的研制和应用提供了契机。对于以角膜缘干细胞缺乏或功能障碍为特征的疾病也有治疗效果。采取角膜缘干细胞移植应是一种合理有效的治疗手段。本文主要介绍了兔角膜缘干细胞的体外分离、培养、鉴定及一些生长因子对其增殖的影响。
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| 关 键 词： | 兔角膜缘干细胞 体外培养 生长因子 细胞增殖 |
| 文章编号： | 1673-6273（2007）10-1578-04 |
| 修稿时间： | 2007-05-302007-07-30 |
Advances in Rabbit Corneal Limbal Stem Cells |
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| BAI Liang,ZHOU Yu-lai,CHENG Yan,GU Guo-zhen. Advances in Rabbit Corneal Limbal Stem Cells[J]. Progress in Modern Biomedicine, 2007, 7(10): 1578-1581,1593 |
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| Authors: | BAI Liang ZHOU Yu-lai CHENG Yan GU Guo-zhen |
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| Affiliation: | Department of Biochemistry, Insistute of Front Medical Sciences, Jilin University, Changchun 130021, China |
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| Abstract: | At present,corneal transplant is the most effective method to cure corneal disease.But there are fewer donors' corneas.Recently,the establishment of technique of stem cells has provided a chance to develop the tissue engineering cornea.It has therapeutic efficacy to some diseases,such as the shortage of limbus comeae stem cells and function disorder.It is an effective and rea- sonable therapeutic tool to transplant the limbus corneae stem cells.This essay mainly introduces the separation,culture and biological characterization of rabbit corneal limbal stem cells in vitro and the effect of growth factor on proliferation of the cells. |
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| Keywords: | Rabbit corneal limbal stem cell Culture in vitro Growth factor Cell proliferation |
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