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Equilibrium Between Dimeric and Monomeric Forms of Human Epidermal Growth Factor is Shifted Towards Dimers in a Solution
Authors:Akunevich  Anastasia Aleksandrovna  Khrustalev   Vladislav Victorovich  Khrustaleva   Tatyana Aleksandrovna  Poboinev   Victor Vitoldovich  Shalygo   Nikolai Vladimirovich  Stojarov   Aleksander Nicolaevich  Arutyunyan   Alexander Migranovich  Kordyukova   Larisa Valentinovna  Sapon   Yehor Gennadyevich
Affiliation:1.Department of General Chemistry, Belarusian State Medical University, Dzerzhinskogo 83, 220045, Minsk, Belarus
;2.Laboratory of Multiprofile Diagnostics, Institute of Physiology of the National Academy of Sciences of Belarus, Academicheskaya 28, 220072, Minsk, Belarus
;3.Department of Radiation Medicine and Ecology, Belarusian State Medical University, Dzerzhinskogo 83, 220045, Minsk, Belarus
;4.Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Leninskie Gory 1-40, Moscow, Russia, 119991
;5.Centre for Physical and Chemical Investigation Methods, Belarusian State Technological University, Sverdlova 13a, 220006, Minsk, Belarus
;
Abstract:The Protein Journal - An interplay between monomeric and dimeric forms of human epidermal growth factor (EGF) affecting its interaction with EGF receptor (EGFR) is poorly understood. While EGF...
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