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Synthesis and screening of bicyclic carbohydrate-based compounds: a novel type of antivirals |
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| Authors: | Van Hoof Steven Ruttens Bart Hubrecht Idzi Smans Gert Blom Petra Sas Benedikt Van hemel Johan Vandenkerckhove Jan Van der Eycken Johan |
| Institution: | Laboratory for Organic and Bioorganic Synthesis, Department of Organic Chemistry, Ghent University, Krijgslaan 281 (S.4), B-9000 Ghent, Belgium. |
| Abstract: | A small library of bicyclic carbohydrate derivatives was synthesized and screened. A strong and selective activity against cytomegalovirus was found. Structure-activity relationship for this new type of antivirals is discussed. |
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