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The inducers 1,3-diaminopropane and spermidine produce a drastic increase in the expression of the penicillin biosynthetic genes for prolonged time,mediated by the LaeA regulator
Authors:Jorge Martín  Carlos García-Estrada  Katarina Kosalková  Ricardo V Ullán  Silvia M Albillos  Juan-Francisco Martín
Institution:1. INBIOTEC, Instituto de Biotecnología de León, Avda. Real n°. 1, Parque Científico de León, 24006 León, Spain;2. Área de Microbiología, Departamento de Biología Molecular, Universidad de León, Campus de Vegazana s/n, 24071 León, Spain;3. Department of Pharmacology, University Medical Center of the Johannes Gutenberg University, 55131 Mainz, Germany;4. Université Paris Descartes, Sorbonne Paris Cité, Centre National de la Recherche Scientifique, UMR 8192, F-75006 Paris, France;1. Department of Microbiology & Immunology, Georgetown University Medical Center, Washington, DC 20057, United States;2. Department of Dermatology, Tongji Hospital, Tongji Medical College, Huazhong University of Sciences & Technology, Wuhan 430030, China;3. Department of Pathology and Pathophysiology, Shantou University Medical College, Shantou, China;1. Department of Mechanical Engineering, Rowan University, 201 Mullica Hill Road, Glassboro, NJ 08028, USA;2. Department of Civil Engineering, American University of Sharjah, Sharjah 26666, United Arab Emirates;1. Department of Biology, University of Saskatchewan, 112 Science Place, Saskatoon, SK, Canada S7N 5E2;2. Department of Microbiology, Faculty of Pharmacy, Zagazig University, Egypt;3. Department of Chemistry, University of Saskatchewan, 110 Science Place, Saskatoon, SK, Canada S7N 5C9;4. Department of Mathematics and Statistics, University of Saskatchewan, 106 Wiggins Road, Saskatoon, SK, Canada S7N 5E6;1. Department of Chemistry and Biochemistry, Seton Hall University, 400 South Orange Avenue, South Orange, NJ 07079, United States;2. Department of Chemistry and Biochemistry, Queens College, City University of New York, 65-30 Kissena Blvd., Flushing, NY 11367, United States
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