CCK-Containing paraneurons in human adenomatous prostate |
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| Authors: | A Cecio T Cocca M T Masotti E La Mura A Vittoria |
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| Institution: | (1) Dept. of Structures, Functions and Biological Technology, University of Naples, Federico II Via F. Delpino, 1-80137 Naples, Italy;(2) III General Surgery, II Faculty of Medicine, University of Naples, Via F. Delpino, Federico II, 1-80137 Naples, Italy |
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| Abstract: | The presence of CCK-containing neuroendocrine cells in human adenomatous prostates, and the colocalization of CCK together with serotonin in the same cell, have been demonstrated by means of an immunohistochemical technique and by a double labeling immunofluorescent staining. CCK-containing neuroendocrine cells had a focal distribution in the prostates and sometimes showed dendrite-like cytoplasmic processes. The major part of CCK (96.55%) colocalized with serotonin.CCK probably stimulates muscle contraction and endocrine/exocrine secretions in the urogenital tract. |
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| Keywords: | cholecystokinin neuroendocrine cells prostatic adenomas |
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