| 中药抗卵巢癌作用及机制研究新进展 |
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| 引用本文： | 文敏,周欣,赵超,龚小见. 中药抗卵巢癌作用及机制研究新进展[J]. 天然产物研究与开发, 2021, 0(3): 521-533 |
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| 作者姓名： | 文敏 周欣 赵超 龚小见 |
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| 作者单位： | 贵州师范大学贵州省山地环境信息系统与生态环境保护重点实验室;喀斯特山地生态环境保护与资源利用协同创新中心;贵州省药物质量控制及评价技术工程实验室;天然药物质量控制研究中心 |
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| 基金项目： | 贵州省高层次创新人才培养项目(黔科合人才[2015]4003)。 |
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| 摘 要： | 卵巢癌是女性常见的生殖器官恶性肿瘤之一,严重威胁着女性的生殖健康.中药治疗卵巢癌具有多靶点、多途径、毒副作用小等特点,近年来已成为国内外学者的研究热点.本文系统总结了中药复方药、植物药(多糖、黄酮类、生物碱、酚类、萜类、醌类、皂苷、酯类、挥发油、醚类)、动物药及矿物药抗卵巢癌的活性及作用机制,并初步分析了中药有效成分抗...
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| 关 键 词： | 卵巢癌 中药 活性 作用机制 构效关系 |
New advances in research on anti-ovarian cancer effect and mechanism of traditional Chinese medicine |
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| WEN Min,ZHOU Xin,ZHAO Chao,GONG Xiao-jian. New advances in research on anti-ovarian cancer effect and mechanism of traditional Chinese medicine[J]. Natural Product Research and Development, 2021, 0(3): 521-533 |
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| Authors: | WEN Min ZHOU Xin ZHAO Chao GONG Xiao-jian |
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| Affiliation: | (Key Laboratory for Information System of Mountainous Areas and Protection of Ecological Environment,Guizhou Normal University;Collaborative Innovation Center for Karst Mountain Ecological Environmental Protection and Resource Utilization(Project of Education Department of Guizhou Province),Guizhou Normal University;Guizhou Engineering Laboratory for Quality Control&Evaluation Technology of Medicine,Guizhou Normal University;Research Center for Quality Control of Natural Medicine,Guizhou Normal University,Guiyang 550001,China) |
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| Abstract: | Ovarian cancer is one of the common malignant tumors of female reproductive organs,which seriously threatens female reproductive health.The treatment of ovarian cancer with traditional Chinese medicine has the characteristics of multi-target,multi-channel and small side effects,which has become the research focus of scholars at home and abroad in recent years.This paper systematically summarized the anti-ovarian cancer activity and mechanism of Chinese herbal formula,plant medicine(polysaccharides,flavonoids,alkaloids,phenols,terpenes,quinones,saponins,esters,volatile oil,ethers),animal medicine and mineral medicine,furthermore,the structure-activity relationship of the effective ingredients of traditional Chinese medicine against ovarian cancer was preliminarily analyzed,which could provide a reference for the in-depth research and application of anti-ovarian cancer drugs. |
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| Keywords: | ovarian cancer traditional Chinese medicine activity mechanism of action structure-activity relationship |
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