| 野猪Toll 样受体基因的结构和功能鉴定 |
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| 引用本文： | 杨秀芹,李海涛,徐扬,翟春媛,马建章,刘娣. 野猪Toll 样受体基因的结构和功能鉴定[J]. 兽类学报, 2011, 31(4): 428-432 |
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| 作者姓名： | 杨秀芹 李海涛 徐扬 翟春媛 马建章 刘娣 |
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| 作者单位： | 东北农业大学动物科技学院,哈尔滨 150030 |
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| 基金项目： | 国家自然科学基金资助项目(31972007); 中国博士后科学基金特别资助项目(200902426); 哈尔滨市科技创新人才研究专项基金(2008RFQXN018); 黑龙江省自然科学基金项目(200927) |
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| 摘 要： | Toll样受体(Toll-like receptors,TLRs)是介导天然免疫和获得性免疫的病原模式识别受体(Pattern recognition receptor,PRRs),能识别表达在病原微生物上高度保守的病原相关分子模式(Pathogen associated molecular patterns,PAMPs),并通过一定的信号转导途径引起核内相关基因的表达,启动和调节机体的免疫反应。
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| 关 键 词： | 野猪 TLR4/5 克隆 组织表达 |
Structural and functional identification of Toll-like receptor genes in wild boar |
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| YANG Xiuqin,LI Haitao,XU Yang,ZHAI Chunyuan,MA Jianzhang,LIU Di. Structural and functional identification of Toll-like receptor genes in wild boar[J]. Acta Theriologica Sinica, 2011, 31(4): 428-432 |
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| Authors: | YANG Xiuqin LI Haitao XU Yang ZHAI Chunyuan MA Jianzhang LIU Di |
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| Affiliation: | College of Animal Science and Technology,Northeast Agricultural University,Harbin 150030,China |
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| Abstract: | Toll-like receptors(TLRs),which play an important role in the immune responses,are candidate genes for resistance to a large number of diseases in animals.In order to provide more useful information for analyzing the structure and function of TLRs,this study was designed to clone TLR4/5 genes in Wild boar and to characterize their tissue expression patterns using RT-PCR.The complete coding sequences of Wild boar TLR4/5 genes were obtained,and each predicted polypeptide contained important structural domains... |
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| Keywords: | Cloning Tissue expression TLR4/5 Wild boar |
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