1.Dipartimento di Scienze e Tecnologie Biomediche,Università di Udine,Udine,Italy;2.Dipartimento di Biologia and CRIBI Biotech Centre,Università di Padova,Padova,Italy;3.Istituto di Chimica del Riconoscimento Molecolare,Milano,Italy
Abstract:
Background
Estimators of free energies are routinely used to judge the quality of protein structural models. As these estimators still
present inaccuracies, they are frequently evaluated by discriminating native or native-like conformations from large ensembles
of so-called decoy structures.