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Evolutionary distance estimation and fidelity of pair wise sequence alignment

Authors:	Email author" target="_blank">Michael?S?Rosenberg Email author

Institution:	(1) Center for Evolutionary Functional Genomics, The Biodesign Institute, and the School of Life Sciences, Arizona State University, Tempe, AZ 84287-4501, USA

Abstract:	Background Evolutionary distances are a critical measure in comparative genomics and molecular evolutionary biology. A simulation study was used to examine the effect of alignment accuracy of DNA sequences on evolutionary distance estimation.

Keywords:
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