(1) Department of Zoology, University of Florida, Box 118525, 32611-8525 Gainesville, FL, USA
Abstract:
Background
The f factor is a new parameter for accommodating the influence of both the starting and ending states in the rate matrices of
"generalized weighted frequencies" (+gwF) models for sequence evolution. In this study, we derive an expected value for f, starting from a nearly neutral model of weak selection, and then assess the biological interpretation of this factor with
evolutionary simulations.