Effectors of lipoprotein lipase secretion from isolated cardiac muscle cells incubated |
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Authors: | Anthony Cryer Paul Chohan Jill J. Smith |
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Affiliation: | 1. Department of Biochemistry, University College, P.O. Box 78, Cardiff, CF1 1XL, Wales, U.K.;2. Department of Biochemistry, University College, London, WC1E 6BT. U.K. |
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Abstract: | Cycloheximide, colchicine, tunicamycin, glucagon, dibutyryl-3′–5′-cyclic AMP, dexamethasone and hydrocortisone had no effect on the lipoprotein lipase activity associated with rat cardiac muscle cells incubated . However, the steroid hormones and inhibitors affected profoundly the appearance of extracellular enzyme during the incubations. The pattern of effects, was consistent with lipoprotein lipase being a normal secretory product of heart muscle cells. |
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