Effect of prostaglandin E2 upon release of pancreatic somatostatin-like immunoreactivity |
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| Authors: | V. Schusdziarra D. Rouiller V. Harris T. Wasada R.H. Unger |
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| Affiliation: | Veterans Administration Medical Center and The University of Texas Health Science Center at Dallas, Dallas, Texas 75216, USA |
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| Abstract: | Infusion of prostaglandin E2 (1 ug/kg/min) in six normal dogs elicited a greater than two-fold rise in pancreaticoduodenal vein somatostatin-like immunoreactivity. Insulin and glucagon also rose. The results raise the possibility that the function of the canine pancreatic D-cell is under prostaglandinergic influence. |
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