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Effects of pertussis vaccine on the lipid metabolism of hamsters
Authors:Rafael Villalobos-Molina  J.Adolfo García-Saínz
Affiliation:1. Departamento de Bioquímica, Facultad de Medicina, Mexico;2. Departamento de Bioenergética, Centro de Investigaciones en Fisiología Celular; Universidad Nacional Autónoma de México. Apartado Postal 70-600; México 20, D.F., México
Abstract:Administration of pertussis vaccine to hamsters markedly affected their lipid metabolism. Four days after the administration of the vaccine a severe fatty liver was observed. Concomitantly, a rise in the serum levels of free fatty acids, triacylglycerols and ketone bodies was detected. It is suggested that an altered regulation of adipose tissue lipolysis might be at least partially responsible for the observed effects.
Keywords:To whom all correspondence should be addressed.
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