Inhibition of T4 Bacteriophage Multiplication by Superinfecting Ghosts and the Development of Tolerance After Bacteriophage Infection |
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| Authors: | Donna Hardy Duckworth |
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| Affiliation: | Department of Microbiology, University of Virginia School of Medicine, Charlottesville Virginia 22903 |
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| Abstract: | Simultaneous addition of T4 phage and ghosts to host cells prevents infective center formation. Cells which have been infected with phage for less than 2 min are also inhibited by superinfecting ghosts. After this time, a chloramphenicol-inhibitable reaction occurs which causes the phage-infected cells to become increasingly tolerant of added ghosts. |
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