Apoptosis and expression of proliferative proteins in the developing nervous system and orofacial region of human embryos |
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| Authors: | Cernochová D Pospísilová E Nepozitková D Havelka P Lichnovský V |
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| Affiliation: | Department of Histology and Embryology, Palacky University, Olomouc, Czech Republic. |
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| Abstract: | We have studied expression of PCNA and Ki-67 in the developing nervous system, sensory organs and orofacial regions in human embryos and fetuses, using monoclonal antibodies PC-10 and MIB-1 in three-step immunohistochemical method and apoptosis performed by TUNEL technique. Expression of PCNA and Ki-67 increased with the age. Apoptosis was rare in above mentioned regions. |
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