Some nutritional factors influencing mevinolin production byAspergillus terreus strain

Aspergillus terreus produces the hypocholesterolemic compound mevinolin. Its growth and mevinolin production were affected by the composition of the culture medium. Both were at a maximum with glucose (6%) as the sole carbon source and in the presence of a mixture of yeast extract and sodium nitrate as nitrogen source. Influence of the concentration of some inorganic salts are also discussed.