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真菌中赖氨酸生物合成途径研究进展
引用本文:蒋佩钰,尚晓冬,宋春艳,王瑞娟,于海龙,李巧珍,章炉军,刘建雨,谭琦. 真菌中赖氨酸生物合成途径研究进展[J]. 微生物学通报, 2020, 47(3): 915-922
作者姓名:蒋佩钰  尚晓冬  宋春艳  王瑞娟  于海龙  李巧珍  章炉军  刘建雨  谭琦
作者单位:1 上海市农业科学院食用菌研究所国家食用菌工程技术研究中心 上海 201403;2 上海海洋大学食品学院 上海 201306,1 上海市农业科学院食用菌研究所国家食用菌工程技术研究中心 上海 201403,1 上海市农业科学院食用菌研究所国家食用菌工程技术研究中心 上海 201403,1 上海市农业科学院食用菌研究所国家食用菌工程技术研究中心 上海 201403,1 上海市农业科学院食用菌研究所国家食用菌工程技术研究中心 上海 201403,1 上海市农业科学院食用菌研究所国家食用菌工程技术研究中心 上海 201403,1 上海市农业科学院食用菌研究所国家食用菌工程技术研究中心 上海 201403,1 上海市农业科学院食用菌研究所国家食用菌工程技术研究中心 上海 201403,1 上海市农业科学院食用菌研究所国家食用菌工程技术研究中心 上海 201403
基金项目:上海市市级农口系统青年人才成长计划项目[沪农青字(2017)第1-13号];上海市农业科学院卓越团队建设计划资助[2017(A-02)]
摘    要:本文综述了真菌中赖氨酸的生物合成途径及途径中的关键基因——酵母氨酸脱氢酶基因,详细介绍了赖氨酸从头合成途径,阐述了酵母氨酸脱氢酶的作用机理及理化性质,以期为探索赖氨酸合成途径及途径中的基因提供资料和思路。

关 键 词:真菌  赖氨酸生物合成  酵母氨酸脱氢酶

Advances in studies on lysine biosynthesis pathway in fung
JIANG Pei-Yu,SHANG Xiao-Dong,SONG Chun-Yan,WANG Rui-Juan,YU Hai-Long,LI Qiao-Zhen,ZHANG Lu-Jun,LIU Jian-Yu and TAN Qi. Advances in studies on lysine biosynthesis pathway in fung[J]. Microbiology China, 2020, 47(3): 915-922
Authors:JIANG Pei-Yu  SHANG Xiao-Dong  SONG Chun-Yan  WANG Rui-Juan  YU Hai-Long  LI Qiao-Zhen  ZHANG Lu-Jun  LIU Jian-Yu  TAN Qi
Affiliation:1 Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, National Research Center of Edible Fungi Biotechnology and Engineering, Shanghai 201403, China;2 College of Food Science & Technology, Shanghai Ocean University, Shanghai 201306, China,1 Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, National Research Center of Edible Fungi Biotechnology and Engineering, Shanghai 201403, China,1 Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, National Research Center of Edible Fungi Biotechnology and Engineering, Shanghai 201403, China,1 Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, National Research Center of Edible Fungi Biotechnology and Engineering, Shanghai 201403, China,1 Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, National Research Center of Edible Fungi Biotechnology and Engineering, Shanghai 201403, China,1 Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, National Research Center of Edible Fungi Biotechnology and Engineering, Shanghai 201403, China,1 Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, National Research Center of Edible Fungi Biotechnology and Engineering, Shanghai 201403, China,1 Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, National Research Center of Edible Fungi Biotechnology and Engineering, Shanghai 201403, China and 1 Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, National Research Center of Edible Fungi Biotechnology and Engineering, Shanghai 201403, China
Abstract:This review summarizes the biosynthesis pathway of lysine in fungi and the key gene in the pathway, saccharopine dehydrogenase. The de novo synthesis pathway of lysine was introduced in detail, and the mechanism and physicochemical properties of saccharopine dehydrogenase was described, which are aimed to provide information and ideas for exploring lysine biosynthesis pathway and genes in the pathway.
Keywords:Fungi   Lysine biosynthesis   Saccharopine dehydrogenase
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