Cryo-electron microscopy of the giant Mimivirus |
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Authors: | Xiao Chuan Chipman Paul R Battisti Anthony J Bowman Valorie D Renesto Patricia Raoult Didier Rossmann Michael G |
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Affiliation: | Department of Biological Sciences, Purdue University, 915 W. State Street, West Lafayette, IN 47907-2054, USA. |
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Abstract: | Mimivirus is the largest known virus. Using cryo-electron microscopy, the virus was shown to be icosahedral, covered by long fibers, and appears to have at least two lipid membranes within its protein capsid. A unique vertex, presumably for attachment and infection of the host, can be seen for particles that have a suitable orientation on the micrographs. |
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Keywords: | Mimivirus cryoEM structure nucleocytoplasmic dsDNA unique vertex |
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