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Cryo-electron microscopy of the giant Mimivirus
Authors:Xiao Chuan  Chipman Paul R  Battisti Anthony J  Bowman Valorie D  Renesto Patricia  Raoult Didier  Rossmann Michael G
Institution:Department of Biological Sciences, Purdue University, 915 W. State Street, West Lafayette, IN 47907-2054, USA.
Abstract:Mimivirus is the largest known virus. Using cryo-electron microscopy, the virus was shown to be icosahedral, covered by long fibers, and appears to have at least two lipid membranes within its protein capsid. A unique vertex, presumably for attachment and infection of the host, can be seen for particles that have a suitable orientation on the micrographs.
Keywords:Mimivirus  cryoEM  structure  nucleocytoplasmic dsDNA  unique vertex
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