Crystallization and preliminary X-ray diffraction analysis of PD-L1, a highly glycosylated ribosome inactivating protein with DNase activity |
| |
Authors: | Ruggiero Alessia Chambery Angela Di Maro Antimo Mastroianni Antonietta Parente Augusto Berisio Rita |
| |
Affiliation: | Istituto di Biostrutture e Bioimmagini, CNR, I-80134 Napoli, Italy. |
| |
Abstract: | PD-L1 is a highly glycosylated type 1 ribosome inactivating protein, from Phytolacca dioica leaves, with the peculiarity to act also as a DNase. PD-L1 has been successfully crystallized using vapour diffusion and seeding techniques. Crystals belong to the monoclinic C2 space group, with unit cell dimensions a=161.01, b=34.73, c=120.63 A, beta=127.99 degrees . Two molecules are present in the asymmetric unit. Phase determination has been achieved using molecular replacement. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|