Identification of specificityH-2.7 as an erythrocyte antigen: Control by an independent locus,H-2G,between theS andD regions |
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Authors: | Chella S. David Jack H. Stimpfling Donald C. Shreffler |
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Affiliation: | (1) Department of Human Genetics, University of Michigan, 48104 Ann Arbor, Michigan;(2) McLaughlin Research Institute, Columbus Hospital, 59401 Great Falls, Montana |
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Abstract: | SpecificityH-2.7 is expressed predominantly on erythrocytes and controlled by a gene that maps within theH-2 gene complex at a locus, designated asH-2G, which apparently lies between regionsS andD. Three phenotypes have been observed with respect to this antigen: a) positive by direct test and absorption (haplotypesH-2f,H-2j,H-2p,H-2s); b) positive only by absorption (H-2k); and c) negative (H-2b,H-2d,H-2q). New crossover positions have been established for severalH-2 recombinants based on classifications for theH-2G locus. |
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