Zinc, copper and iron concentrations in cerebral cortex of male rats exposed to formaldehyde inhalation |
| |
Authors: | Ouz Aslan
zen Ahmet Songur Mustafa Sarslmaz Mehmet Yaman Iter Ku |
| |
Institution: | Karaelmas University, Faculty of Medicine, Department of Anatomy, Zonguldak, Turkey. oaslano@hotmail.com |
| |
Abstract: | Retrospective cohort studies and clinical findings have suggested effects of formaldehyde exposure on the central nervous system in anatomists, embalmers and pathologists. On the other hand, harmful effects of formaldehyde inhalation on the nervous system are not well documented. The concentrations of elements such as zinc, copper and iron within the cerebral cortex indicate whether physiological conditions are maintained. In this study, adult male albino Wistar rats were exposed to formaldehyde at different concentrations (0; 6.1; 12.2 mg x m(-3)) and during different periods of time (subacute-subchronic), and body weights were recorded weekly. Zinc, copper and iron concentrations were measured in the parietal cortex using atomic absorption spectrometry after wet ashing. We conclude that subacute or subchronic exposure to formaldehyde may cause growth retardation and alter zinc, copper and iron levels in the cerebral cortex. |
| |
Keywords: | formaldehyde exposure inhalation cerebral cortex zinc copper iron |
本文献已被 ScienceDirect 等数据库收录! |
|