Refined algorithm and computer program for calculating all non-negative fluxes admissible in steady states of biochemical reaction systems with or without some flux rates fixed

A refined algorithm together with a computer procedure for determiningthe complete set of non–negative, steady–state fluxesin biochemical reaction systems of any complexily, with or withoutsome flux rates fixed, is given. It is shown that this set isa convex polyhedron, which may or may not be bounded. The algorithmis illustrated by several examples; one of them concerns intermediarymetabolism. A computer cade in standard C is presented.