Localization of mouse melanoma growth stimulatory activity gene (Mgsa) between Afp and Gus on chromosome 5 using interspecific backcross mice |
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| Authors: | M F Seldin L Martinez T A Howard S L Naylor A Y Sakaguchi |
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| Affiliation: | Department of Medicine, Duke University Medical Center, Durham, NC 27710. |
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| Abstract: | Melanoma growth stimulatory activity (Mgsa) is a polypeptide mitogen and a possible autocrine growth factor for melanoma and other tumor cells. A restriction fragment length variant of Mgsa was followed in interspecific backcross mic Mgsa was localized between Afp and Gus on mouse chromoson 5, distal to known loci affecting skin pigmentation. |
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