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Extracellular formation of 5-aminolevulinic acid by intact cells of the marine photosynthetic bacterium Rhodovulum sp. under various pH conditions |
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| Authors: | Noparatnaraporn Napavarn Watanabe Masanori Sasaki Ken |
| Affiliation: | (1) Department of Microbiology, Faculty of Science, Kasetsart University, Bangkok, 10900, Thailand;(2) Hiroshima Kokusai Gakuin University, 6-20-1 Nakano, Akiku, Hiroshima, 739-0321, Japan |
| Abstract: | Extracellular formation of 5-aminolevulinic acid (ALA) by Rhodovulum sp. PS88 correlated with the consumption of the undissociated form of levulinic acid (LA) in an intact cell system. The concentration of the undissociated form of LA governed the extracellular formation of ALA at various culture pH values. This phenomenon might be caused by inhibition of ALA dehydratase by the undissociated form of LA after uptake into the cells as observed in Rhodobacter sphaeroides. |
| Keywords: | ALAD ALA formation effect of pH intact cell system undissociated form of LA |
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