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An expedited approach for sustained delivery of bone morphogenetic protein‐7 to bone defects using gene activated fragments of subcutaneous fat
Authors:Volker M Betz  Oliver B Betz  Tom Rosin  Alexander Keller  Christian Thirion  Michael Salomon  Suzanne Manthey  Peter Augat  Volkmar Jansson  Peter E Müller  Stefan Rammelt  Hans Zwipp
Institution:1. Department of Trauma and Reconstructive Surgery and Center for Translational Bone, Joint and Soft Tissue Research, University Hospital Carl Gustav Carus Dresden, TU Dresden, Dresden, Germany;2. Department of Orthopedic Surgery, Physical Medicine and Rehabilitation, University Hospital Grosshadern, Ludwig‐Maximilians‐University Munich, Munich, Germany;3. Sirion Biotech GmbH, Martinsried, Germany;4. Institute of Biomechanics, Trauma Center Murnau, Murnau, Germany;5. Paracelsus Medical University, Salzburg, Austria
Abstract:
Keywords:BMP‐7  bone defect  bone regeneration  fat tissue  gene therapy  tissue engineering
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