Type III secretion gets an LcrV tip |
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Authors: | Mota Luís Jaime |
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Affiliation: | Centre for Molecular Microbiology and Infection, Imperial College London, Flowers Building, Armstrong Road, London, UK, SW7 2AZ. j.mota@imperial.ac.uk |
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Abstract: | Type III secretion is used by many Gram-negative pathogenic bacteria to inject effector proteins into eukaryotic host cells. Effector delivery requires a secretion apparatus, called an injectisome or needle complex, and the assembly of a translocation pore in a target-cell membrane. Recent work provides evidence that enlightens the view of how pore assembly might occur and of how the injectisome and the pore might be linked. |
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