Synthesis of unusual thick pili by Escherichia coli of EPEC serogroup O119 |
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Authors: | David E Bradley Christine R Thompson |
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Institution: | Faculty of Medicine, Memorial University of Newfoundland, St. John's, Newfoundland, Canada. |
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Abstract: | Unique very thick pili were found in varying numbers on cells of five out of 11 clinical isolates of enteropathogenic Escherichia coli belonging to the classic EPEC serogroup O119. They were approximately 12.5 nm in diameter, which is thicker than any other known E. coli pilus type. Analysis of the plasmid profiles of the O119 isolates showed that one strain was plasmid-free while the remainder contained numerous plasmids with a wide range of sizes. The thick pilus determinants were located on a 140-kb non-transferrable plasmid. They were not associated with adherence or a putative 90-kb enteroadherence factor plasmid. |
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Keywords: | Pili Diarrhoeagenic Escherichia coli |
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