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旋覆花的化学成分研究(英文)
引用本文:覃江江,朱佳娴,朱燕,严岚,金慧子,张卫东. 旋覆花的化学成分研究(英文)[J]. 天然产物研究与开发, 2011, 23(6): 999-1001
作者姓名:覃江江  朱佳娴  朱燕  严岚  金慧子  张卫东
作者单位:1. 上海交通大学药学院,上海,200240
2. 上海交通大学药学院,上海200240;第二军医大学药学院,上海200433
基金项目:supported by the Scientific Foundation of Shanghai China(08DZ1971302)
摘    要:通过应用硅胶柱色谱,Sephadex LH-20柱色谱,以及高效液相制备色谱等手段,从旋覆花地上部分分离纯化得到10个化合物,再通过光谱学方法,并结合化合物的理化性质鉴定为泽兰内酯(1)、7-羟基香豆素(2)、瑞香素(3)、东莨菪素(4)、蟛蜞菊内酯(5)、枸橼苦素(6)、杜仲树脂酚(7)、丁香酸(8)、香草酸(9)和异丁香酸(10)。化合物1~10均为首次从旋覆花属植物中分离得到。

关 键 词:旋覆花  化学成分  香豆素类化合物

Chemical Constituents from the Aerial Parts of Inula japonica Thunb
QIN Jiang-jiang,ZHU Jia-xian,ZHU Yan,YAN Lan,JIN Hui-zi,ZHANG Wei-dong. Chemical Constituents from the Aerial Parts of Inula japonica Thunb[J]. Natural Product Research and Development, 2011, 23(6): 999-1001
Authors:QIN Jiang-jiang  ZHU Jia-xian  ZHU Yan  YAN Lan  JIN Hui-zi  ZHANG Wei-dong
Affiliation:QIN Jiang-jiang1,ZHU Jia-xian1,ZHU Yan1,YAN Lan1,JIN Hui-zi1,ZHANG Wei-dong1,2 1School of Pharmacy,Shanghai Jiao Tong University,Shanghai 200240,China,2School of Pharmacy,Second Military Medical University,Shanghai 200433
Abstract:Ten compounds were isolated and purified by column chromatography with silica gel,Sephadex LH-20 and preparative HPLC from the aerial parts of Inula japonica Thunb..On the basis of physicochemical properties and spectroscopic data,their structures were identified as ayapin(1),7-hydroxycoumarin(2),daphnetin(3),scopoletin (4),wedelolactone(5),citrusin C(6),medioresinol(7),syringic acid(8),vanillic acid(9),and isovanillic acid(10). Compounds 1-10 were isolated from I.japonica for the first time.
Keywords:Inula japonica Thunb  chemical constituents  coumarin
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