Serum prealbumin in inbred strains of Mus musculus |
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| Authors: | Larry Claxton H. V. Malling H. E. Walburg |
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| Affiliation: | 1. Mutagenesis Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina
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| Abstract: | Separation of blood serum prealbumin from ten strains of inbred mice was accomplished using acrylamide electrophoresis. Nine of these strains demonstrated the same five prealbumin bands; however, the C57BL/6JWg strain showed a sixth band. The use of appropriate crosses of C57BL/6JWg and DBA/2fWg showed this unique band to be the product of a single autosomal dominant gene. We have named the gene for this prealbumin band Pre-1 and have shown a map distance between Pre-1 and b of 2.25 cM. Only one of the five prealbumins present in all strains of mice tested showed nonspecific esterase activity. |
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