Histomorphometric changes in the placenta and umbilical cord during complications of pregnancy |
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| Authors: | D Güven BZ Altunkaynak G Altun I Alkan ? Kocak |
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| Institution: | 1. Department of Obstetrics and Gynecology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkeyberrinzuhal@gmail.com;3. Department of Histology and Embryology, Faculty of Medicine, Okan University, ?stanbul, Turkey;4. Department of Histology and Embryology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey;5. Department of Obstetrics and Gynecology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey |
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| Abstract: | Pregnancy complications may cause morphological changes and circulation defects in the placenta, which may lead to morbidity and mortality in fetuses and newborns. We investigated structural changes in the placenta and umbilical cord under various abnormal maternal conditions. Placenta and umbilical cord specimens were obtained from pregnant women during labor at 37 ? 42 weeks gestation. Volumetric measurements were made for each placenta and umbilical cord using the Cavalieri method. Significant differences were observed for volumetric densities of total villi, syncytial knots, intervillous vessels and perivillous fibrin deposition. We observed particular increases in the volumetric parameters of the pre-eclampsia group compared to the other groups. The tunica media of the umbilical arteries was increased significantly with intrahepatic cholestasis. |
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| Keywords: | apoptosis morphometry placenta pregnancy complications stereology umbilical cord |
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