Mutations in Leptin (LEP) Gene Are Associated with Carcass and Meat Quality Traits in Crossbreed Rabbits |
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| Authors: | Lukasz Migdal Konrad Koziol Sylwia Palka Wladyslaw Migdal Tomasz Zabek Agnieszka Otwinowska-Mindur |
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| Affiliation: | 1. Department of Genetics and Animal Breeding, Faculty of Animal Sciences, University of Agriculture in Krakow, Krakow, Poland;2. Department of Animal Product Technology, Faculty of Food Technology, University of Agriculture in Krakow, Krakow, Poland;3. Department of Genomics and Animal Molecular Biology, National Research Institute of Animal Production Poland |
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| Abstract: | Leptin is a hormone synthesized and secreted primarily in adipose cells that help to regulate energy balance. This study examined the associations of single nucleotide polymorphisms in the rabbit leptin gene with growth traits, slaughter traits and physicochemical parameters of New Zealand White (NZW) and Belgian Giant Grey (BGG) crossbreed rabbits. In total, 320 crossbreed animals were genotyped for polymorphisms within exon 2—g.16081633T>C, intron 1_2—g.16081420C>T, and within UTR—g.16079636C>G for association analysis. Identified polymorphisms within rabbits leptin gene showed significant differences for dissectible fat percentage in carcass and dissectible fat weight in intermediate part (g.16081633T>C). Moreover, meat traits like protein content (g.16081633T>C; g.16079636C>G), intramuscular fat content (g.16081633T>C; g.16079636C>G, g.16081420C>T), dry matter (g.16081420C>T), ash (g.16081420C>T), water (g.16081420C>T), and cohesiveness (g.16081420C>T, g.16079636C>G) were affected by polymorphisms in leptin gene. We conclude that polymorphism in the rabbit leptin gene influences important carcass and meat traits of NZW?×?BGG crossbreeds. Therefore, polymorphisms identified in this study may be used in selection as a meat trait markers. |
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| Keywords: | Fatness traits meat traits rabbits SNPs |
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