腮腺肿瘤患者行游离保留SMAS术后的复发及预后影响因素分析

摘要 目的：探讨腮腺肿瘤患者行游离保留SMAS术后的复发及预后影响因素分析。方法：以我院2016年3月-2022年1月收治的60例腮腺肿瘤患者作为研究对象。所有患者均行游离保留SMAS联合全腮腺切除术治疗。术后进行随访。采用χ²检验和独立样本t检验进行腮腺肿瘤患者预后复发及预后存活情况的亚组分析。采用Pearson检验进行相关性分析；采用Cox回归模型计算腮腺肿瘤患者预后的独立危险因素。结果：复发和未复发患者性别、年龄、BMI、糖尿病病史和高血压病史无显著差异（P＞0.05）；复发和未复发患者的淋巴结转移、病理类型、TNM分期、AJCC临床分期差异显著（P<0.05）；预后死亡和预后存活患者性别、年龄、BMI、糖尿病病史和高血压病史无显著差异（P＞0.05）；预后死亡和预后存活患者的淋巴结转移、病理类型、TNM分期、AJCC临床分期和复发情况差异显著（P<0.05）；淋巴结转移、病理类型、TNM分期、复发、AJCC临床分期与腮腺肿瘤患者预后存活情况密切相关（P<0.05）；多因素Cox分析结果显示，淋巴结转移、病理类型、TNM分期、复发、AJCC临床分期是独立危险因素（P<0.05）。结论：疾病相关因素是导致腮腺恶性肿瘤患者复发和死亡的重要因素，临床早期可针对性调整治疗方案以降低患者术后复发和恶性肿瘤。

Analysis of Recurrence and Prognostic Factors after Free SMAS Retention in Parotid Gland Tumors

ABSTRACT Objective: To investigate the recurrence and prognostic factors of parotid tumors after free retention SMAS. Methods: 60 patients with parotid gland tumor admitted to our hospital from March 2016-January 2022 were selected as the research objects. All patients were treated with free retention SMAS combined with total parotidectomy. postoperative follow-up was performed. Chi-square test and independent sample t test were used to analyze the recurrence and survival of parotid tumors. Pearson test was used for correlation analysis. Cox regression model was used to calculate the independent prognostic risk factors of parotid gland tumors. Results: There were no significant differences in gender, age, BMI, history of diabetes and hypertension between patients with and without recurrence (P>0.05). There were significant differences in lymph node metastasis, pathological type, TNM stage and AJCC clinical stage between patients with and without recurrence (P>0.05). There were no significant differences in gender, age, BMI, history of diabetes and hypertension between prognosis death and prognosis survival (P>0.05). There were significant differences in lymph node metastasis, pathological type, TNM stage, AJCC clinical stage and recurrence between death and survival patients (P>0.05). Lymph node metastasis, pathological type, TNM stage, recurrence and AJCC clinical stage were closely correlated with the prognosis and survival of parotid tumors (P>0.05). Multivariate Cox analysis showed that lymph node metastasis, pathological type, TNM stage, recurrence and AJCC clinical stage were independent risk factors (P>0.05). Conclusion: Disease-related factors are important factors leading to the recurrence and death of parotid gland malignant tumor patients. In early clinical stage, targeted adjustment of treatment can reduce postoperative recurrence and malignant tumor.