| Does ornithine stimulate carbamoylphosphate synthetase? |
| |
| 摘 要： |
|
| 收稿时间： | 1984-06-11 |
Does ornithine stimulate carbamoylphosphate synthetase? |
| |
| G Banko,H Zollner. Does ornithine stimulate carbamoylphosphate synthetase?[J]. The International journal of biochemistry, 1985, 17(4): 503-507. DOI: 10.1016/0020-711X(85)90146-6 |
| |
| Authors: | G Banko H Zollner |
| |
| Abstract: | The effect of ornithine on carbamoylphosphate formation of rat liver mitochondria treated with Triton X 100 was studied. The rate of carbamoylphosphate accumulation and citrulline formation depended on the ATP-, Pi-, N-acetylglutamate and protein concentration. At optimal conditions the rate of citrulline formation was at least 1.5-fold higher than the rate at which carbamoylphosphate accumulated (ornithine absent). A significant correlation between the amount of carbamoylphosphate formed and the citrulline/carbamoylphosphate ratio (ornithine effect) was found. In mitochondria the presence of a carbamoylphosphate degrading enzyme could be demonstrated. This enzyme may be one factor for the differences in the rate of carbamoylphosphate accumulation and the rate of citrulline synthesis. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
