Putative lipoproteins identified by bioinformatic genome analysis of Leifsonia xyli ssp. xyli, the causative agent of sugarcane ratoon stunting disease |
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| Authors: | IAIN C SUTCLIFFE MATTHEW I HUTCHINGS |
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| Institution: | Biomolecular and Biomedical Research Centre, School of Applied Sciences, Ellison Building, Northumbria University, Newcastle upon Tyne NE1 8ST, UK;
School of Biological Sciences and School of Medicine, Health Policy and Practice, University of East Anglia, UK |
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| Abstract: | Leifsonia xyli ssp. x yli is the causative agent of ratoon stunting disease, a major cause of economic loss in sugarcane crops. Understanding of the biology of this pathogen has been hampered by its fastidious growth characteristics in vitro . However, the recent release of a genome sequence for this organism has allowed significant novel insights. Further to this, we have performed a bioinformatic analysis of the lipoproteins encoded in the L. xyli genome. These analyses suggest that lipoproteins represent c . 2.0% of the L. xyli predicted proteome. Functional analyses suggest that lipoproteins make an important contribution to the physiology of the pathogen and may influence its ability to cause disease in planta . |
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