Synthesis of some new 2-alpha-L-arabinopyranosyl-1,2,4-triazines as potential antitumor chemotherapeutics |
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| Authors: | Mansour Abdel Kader Eid Mohga M Khalil Nasser S A M |
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| Affiliation: | Department of Chemistry, Faculty of Science, Cairo University, Giza, Egypt. |
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| Abstract: | Synthetic routes towards different 2-alpha-L-arabinopyranosyl-3-thioxo-2,3-dihydro-1,2,4-triazin-5(4H)-/ones or thiones were investigated. Primary human anticancer screening of two selected compounds resulted in an active compound against SF-268 (CNS) cell line. |
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